Clinical Study
The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project
Table 7
Correlation measures using Spearman rank correlation coefficient measures between the various variables and fatigue scores.
| Variable | | |
| Age | — | N.S. | UPDRS domain 3 | −0.2380 | =0.0064 | UPDRS domain 4 | −0.1968 | 0.0237 | CIRS total | — | N.S. | CIRS domain 1 | — | N.S. | HADS anxiety domain | −0.3948 | <0.0001 | HADS depression domain | −0.4171 | <0.0001 | Frontal assessment battery | 0.3374 | =0.0001 | NMSQuest total | −0.3122 | =0.0003 | NMSQuest sleep domain | −0.2823 | =0.0009 | Other NMSQuest domains | — | N.S. | Hoehn & Yahr staging | −0.2882 | =0.0007 | PDQ-8 | −0.367 | <0.0001 | NMSS total | −0.3924 | <0.0001 | NMSS cardiovascular domain | −0.2985 | =0.0004 | NMSS sexual function domain | −0.2576 | =0.003 | NMSS sleep domain | −0.3908 | <0.0001 | NMSS mood domain | −0.3766 | <0.0001 | NMSS attention/memory domain | −0.2574 | =0.003 | NMSS misc. domain | −0.2666 | 0.002 | Other NMSS domains | — | N.S. |
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The key correlations () are highlighted (N.S.: not significant, UPDRS: unified Parkinson’s disease rating scale, CIRS: cognitive impairment rating scale, HADS: hospital anxiety and depression scale, NMSQuest: nonmotor symptom questionnaire, NMSS: nonmotor symptom scale).
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