Clinical Study

The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project

Table 7

Correlation measures using Spearman rank correlation coefficient measures between the various variables and fatigue scores.

Variable

AgeN.S.
UPDRS domain 3−0.2380=0.0064
UPDRS domain 4−0.19680.0237
CIRS totalN.S.
CIRS domain 1N.S.
HADS anxiety domain−0.3948<0.0001
HADS depression domain−0.4171<0.0001
Frontal assessment battery0.3374=0.0001
NMSQuest total−0.3122=0.0003
NMSQuest sleep domain−0.2823=0.0009
Other NMSQuest domainsN.S.
Hoehn & Yahr staging−0.2882=0.0007
PDQ-8−0.367<0.0001
NMSS total−0.3924<0.0001
NMSS cardiovascular domain−0.2985=0.0004
NMSS sexual function domain−0.2576=0.003
NMSS sleep domain−0.3908<0.0001
NMSS mood domain−0.3766<0.0001
NMSS attention/memory domain−0.2574=0.003
NMSS misc. domain−0.26660.002
Other NMSS domainsN.S.

The key correlations ( ) are highlighted (N.S.: not significant, UPDRS: unified Parkinson’s disease rating scale, CIRS: cognitive impairment rating scale, HADS: hospital anxiety and depression scale, NMSQuest: nonmotor symptom questionnaire, NMSS: nonmotor symptom scale).