Protective Role of rAAV-NDI1, Serotype 5, in an Acute MPTP Mouse Parkinson's Model

Figure 5

Evaluation of MPTP effects on the DAergic neurons of the striatum using mouse brain homogenates. (a) Representative Western blots, 60 μg of protein per lane was loaded on a 10% SDS-PAGE gel, (b) statistical analysis of western blots for each treatment group MPTP Only (MO), NDI1 + Saline (NS), and NDI1 + MPTP (NM), VMAT2 (𝑛=7,7,10), DAT (𝑛=8,8,11), TH (𝑛=5,5,7), and NDI1 (𝑛=0,9,13). ^∗∗=𝑃<.005, ^∗∗∗=𝑃<.00001. Light grey column, left hemisphere; dark grey column, right hemisphere.

(a)

(b)