Research Article

A Perfusion MRI Study of Emotional Valence and Arousal in Parkinson’s Disease

Table 4

CBF correlates with emotional arousal.
(a) Clusters in the brain in which CBF correlates positively with emotional arousal

FDR-corrected P valueNumber of voxelsPeak T value (22 d.f.)Coordinates of peak T valueSide of brainAnatomical description of cluster

0.039843.0031.5, −9, −6RightPutamen, thalamus (ventrolateral), hippocampus
0.039853.00−34.5, −75, 6LeftMiddle temporal gyrus (BA 39), middle occipital gyrus (BA 19)
<0.00052313.00−37.5, −57, 45LeftInferior parietal lobule (BA 40), superior occipital gyrus (BA 19)
0.0391003.0034.5, −57, 39RightInferior parietal lobule (BA 40), superior parietal lobule and precuneus (BA 7)

(b) Clusters in the brain in which CBF correlates negatively with emotional arousal

FDR-corrected P valueNumber of voxelsPeak T value (22 d.f.)Coordinates of peak T valueSide of brainAnatomical description of cluster

0.0012163.00−34.5, −27, 27LeftStriatum and nearby white matter, thalamus (medial dorsal), insula (BA 13)
0.0151103.00−34.5, −60, 57LeftPrecuneus and superior parietal lobule (BA 7)
0.0051393.00−25.5, −6, −9LeftPutamen, claustrum, insula (BA 13), amygdala-striatal transition area, superior temporal gyrus (BA 22, 38), inferior frontal gyrus (BA 47)—ventral frontal part
<10−75773.0013.5, −45, −6RightSuperior and middle occipital gyrus, cuneus (BA 17, 18, 19), posterior cingulate cortex (BA 23), thalamus (medial dorsal), midbrain (central portion and red nucleus)
0.0051493.0034.5, −81, 39RightSuperior parietal lobule and precuneus (BA 7)

No voxels passed the predefined voxel-level threshold of . For hypothesis generation, we repeated our analysis using a voxel-level threshold of , and those results are shown here.
Note: only clusters significant after correction for multiple comparisons are shown here.