Parkinson’s Disease / 2011 / Article / Tab 1

Research Article

Effects of Human Alpha-Synuclein A53T-A30P Mutations on SVZ and Local Olfactory Bulb Cell Proliferation in a Transgenic Rat Model of Parkinson Disease

Table 1

Quantification of BrdU positive cells and layer’s volume in wild-type and transgenic rats from the olfactory bulb glomerular and granular cell layers and in the SVZ. Mean ± SEM. * ; ns: no statistical difference between the 2 groups. Only the number of BrdU positive cells in the glomerular layer of transgenic rats was significantly increased by 68% as compared to WT animals. Values are expressed as density per mm3 and total number of BrdU positive neurons.

Wild-type groupTransgenic group

Glomerular layer density in mm3 *
Glomerular layer total number *
Granular cell layer density in mm3 ns
Granular cell layer total number ns
Subventricular zone total number ns
Glomerular layer volume in mm3 ns
Granular layer volume in mm3 ns

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