Effects of Human Alpha-Synuclein A53T-A30P Mutations on SVZ and Local Olfactory Bulb Cell Proliferation in a Transgenic Rat Model of Parkinson Disease
Quantification of BrdU positive cells and layer’s volume in wild-type and transgenic rats from the olfactory bulb glomerular and granular cell layers and in the SVZ. Mean ± SEM. *; ns: no statistical difference between the 2 groups. Only the number of BrdU positive cells in the glomerular layer of transgenic rats was significantly increased by 68% as compared to WT animals. Values are expressed as density per mm3 and total number of BrdU positive neurons.
Glomerular layer density in mm3
Glomerular layer total number
Granular cell layer density in mm3
Granular cell layer total number
Subventricular zone total number
Glomerular layer volume in mm3
Granular layer volume in mm3
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