Clinical Study

Neuropsychiatric Symptoms in Parkinson's Disease with Mild Cognitive Impairment and Dementia

Table 3

Neuropsychological test scores for the PD groups without cognitive impairment and with mild cognitive impairment, and the healthy control group.


PDPD
Statistic  ( 𝐹 or 𝜒 2 );
𝑃   value
No cognitive
Mild cognitive
Healthy
control  
impairmentimpairment(HC; 𝑛 = 3 3 )
(PD-NC; 𝑛 = 5 4 )(PD-MC; 𝑛 = 4 8 )

Mean (SD)

Attention and working memory
 Trails B-Trails A (reaction time in seconds)41.55 (17.41)136.68 (71.30)41.27 (26.23)85.32; <0.001
 Serial 7’s4.65 (0.59)3.78 (1.40)5.09 (0.52)20.65; <0.001
 Digit 𝑛 -back 17.76 (3.24)13.48 (2.76)19.68 (3.09)43.89; <0.001

Executive function
 cWCST totalii39.04 (7.41)32.32 (9.47)40.82 (8.63)11.55; <0.001
 FAS total 47.89 (12.41)34.06 (10.40)52.71 (12.09)26.84; <0.001

Memory
 5-minute recall of three words 2.72 (0.49)2.20 (1.03)2.78 (0.78)7.62; 0.001

Visuospatial function
 Intersecting pentagons0.98 (0.14)0.40 (0.49)1.00 (0)71.95; <0.001

iicWCST: Computerised version of the Wisconsin Card Sorting Test.