Risk of Falls in Parkinson’s Disease: A Cross-Sectional Study of 160 Patients

Table 3

Logistic regression analysis.

	Bivariate analysis			Multivariate analysis
	Odds ratio	95% CI	P value	Odds ratio	95% CI	𝑃 value
Age	1.04	0.99–1.08	0.025	1.04	0.95–1.14	0.381
Disease duration	1.12	1.05–1.19	<0.001	0.96	0.89–1.03	0.326
PD subtype	2.37	1.22–4.60	0.010	2.07	0.89–4.80	0.090
Motor fluctuations	2.81	1.39–5.69	0.004	1.91	0.75–5.62	0.200
Dyskinesia	2.80	1.36–5.78	0.005	0.98	0.33–2.87	0.972
Hoehn and Yahr	3.06	2.04–4.60	<0.001	1.59	0.72–3.50	0.247
UPDRS	1.06	1.03–1.09	<0.001	0.98	0.94–1.04	0.658
FOG	4.42	2.24–8.72	<0.001	1.65	0.67–4.03	0.274
FOG questionnaire	1.15	1.08–1.22	<0.001	1.01	0.89–1.22	0.131
Activities of daily living*	0.96	0.94–0.97	<0.001	1.02	0.92–1.14	0.807
MMSE*	0.91	0.85–0.98	0.017	1.02	0.93–1.13	0.640
Tinetti Balance*	0.80	0.74–0.86	<0.001	0.84	0.74–0.97	0.017
Tinetti Gait*	0.80	0.73–0.87	<0.001	1.13	0.95–1.43	0.256
Tinetti total*	0.89	0.85–0.93	<0.001	0.93	0.87–1.01	0.690
Get-up-and-go	0.95	0.90–1.01	0.189
Levodopa dose	1.002	1.001–1.004	0.005	1.02	0.94–1.19	0.944
COMT-I use	2.80	1.17–6.74	0.021	3.41	1.06–11.37	0.052
Neuroleptic use	12.34	1.48–102.98	0.020	1.25	0.16–12.67	0.854
Cholinesterase inhibitor use	11.92	2.12–12.34	0.002	1.11	0.23–11.78	0.756

Abbreviations. PD: Parkinson disease; UPDRS: Unified Parkinson’s Disease Rating Scale; FOG: freezing of gait; MMSE: Minimental State Examination.
* Functional tests: higher scores means normality.