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Parkinson’s Disease
Volume 2012 (2012), Article ID 469126, 5 pages
http://dx.doi.org/10.1155/2012/469126
Clinical Study

Psychosis Assessment in Early-Stage Parkinson’s Disease: Comparing Parkinson’s Psychosis Questionnaire with the Brief Psychiatric Rating Scale in a Portuguese Sample

1Mental Health and Psychiatry Department, Hospital S. Francisco Xavier (CHLO), Estrada do Forte do Alto do Duque, 1495-005 Lisbon, Portugal
2CEDOC and Department of Mental Health, Faculdade de Ciências Médicas, (FCM), Universidade Nova de Lisboa, (UNL), Campo dos Mártires da Pátria, 130, 1169-056 Lisbon, Portugal
3Neurology Department, Hospital de Egas Moniz (CHLO), Rua da Junqueira 126, 1349-019 Lisbon, Portugal
4CEDOC and Neurology Department, Faculdade de Ciências Médicas, (FCM) Universidade Nova de Lisboa (UNL), Campo dos Mártires da Pátria, 130, 1169-056 Lisbon, Portugal

Received 1 July 2011; Accepted 31 March 2012

Academic Editor: Daniel H. Jacobs

Copyright © 2012 I. Cargaleiro et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Psychotic symptoms in Parkinson’s disease (PD) are frequent, disabling, and an important prognostic factor. Thus, screening instruments for detecting psychosis in PD are needed. For this purpose, we applied the Parkinson’s Psychosis Questionnaire (PPQ), a short structured questionnaire, which requires no specific training, along with the Brief Psychiatric Rating Scale, expanded version (BPRS-E), for rating general psychopathology, including psychotic symptoms. We evaluated, in a cross-sectional study, a Portuguese sample of 36 early-stage PD patients (mean age of 73 years; mean duration of illness of 3.2 years). The PPQ total score correlated with the BPRS-E total score (0.359; 𝑃 = 0 . 0 3 2 ) and with the BPRS-E-positive symptoms score (0.469; 𝑃 = 0 . 0 0 4 ). The prevalence of psychosis (41.7%) was higher than expected. Sampling bias and detection of minor psychotic phenomena may have contributed to this result. These findings suggest that the PPQ should be further evaluated as a feasible assessment for psychotic symptoms in PD.