Dyskinesias and Treatment with Pramipexole in Patients with Parkinson's Disease

Figure 1

Treatment of Parkinson’s disease: anti-Parkinson’s medications modulate key stages of dopaminergic neurotransmission. Abbreviations: TYR: tyrosine, L-DOPA: L-3, 4-dihydroxyphenylalanine, DA: dopamine, MAO: monoamine oxidase, DAT: DA reuptake transporter, COMT: catechol-O-methyltransferase, 3-MT: 3-methoxytyramine, DAR: DA receptor. Anti-Parkinson’s drugs are highlighted in bold. Pointed arrows indicate stimulatory, and closed arrows indicate inhibitory activity.