Importance of the Brain Angiotensin System in Parkinson’s Disease

Table 1

Predominant distributions of the three angiotensin receptor subtypes and the HGF/c-Met receptor identified in mammalian brains.

Subtype	AT1	AT2	AT4	c-Met
Structure
Caudate putamen	+	++	++
Cerebellum	+	+	++	++
Globus pallidus		++	++
Nucleus accumbens			+
Periaqueductal gray			++
Red nucleus			+
Striatum	++		++	++
Substantia nigra	++		+
Ventral tegmental area	++	++	++

Adapted from [15, 22, 30–33]; +: moderate levels of the receptor subtype; ++: high levels of the receptor subtype.