Comparison of the Psychological Symptoms and Disease-Specific Quality of Life between Early- and Typical-Onset Parkinson’s Disease Patients
Table 1
Baseline, clinical, and sociodemographic characteristics of the early-onset and typical-onset Parkinson’s disease patients.
Characteristics
Early onset ()
Typical onset ()
value
Gender no. (%)
Female
17 (37.8)
28 (29.5)
0.326
Male
28 (62.2)
67 (70.5)
Level of education no. (%)
Illiterate
2 (4.7)
10 (10.5)
0.137
Primary and/or secondary
11 (25.6)
24 (25.3)
High School/Diploma
17 (39.5)
21 (22.1)
College and/or University
13 (30.2)
40 (42.1)
Duration of disease (yr)
Mean (SD)
8.5 (7.7)
5.9 (3.7)
UPDRS score mean (SD)
Part I-mental
2.3 (2.8)
1.8 (1.9)
0.407
Part II-ADL
12.5 (7.6)
10.6 (6.8)
0.148
Part III-motor
15.7 (11.5)
15.2 (7.6)
0.490
Part IV-complications
4.0 (3.4)
3.3 (2.4)
0.198
Total
34.3 (21.0)
30.6 (15.2)
0.326
Hoehn and Yahr Stage
Median (IQR)
2.0 (2.0)
2.0 (1.5)
0.923
Schwab and England activities of daily Living Score (%)
Mean (SD)
80.4 (19.6)
82.4 (15.1)
0.553
Levodopa dose (mg) median (IQR)
Cumulative Daily Dose
1000.0 (710.0)
750.0 (500.0)
Weight-adjusted daily dose
13.4 (12.2)
10.4 (6.7)
Difference is statistically significant at the 0.05 level (2-tailed). Data on education level is not available for two patients (missing value) and valid relative percentages are reported.
