Research Article

Orbitofrontal 18F-DOPA Uptake and Movement Preparation in Parkinson’s Disease

Table 2

Results of correlation analysis between mean reaction time (RT) and dopaminergic activity as assessed through 18F-DOPA PET in de novo Parkinson’s disease patients.

AnalysisCluster levelPeak level
Cluster extentCorrected valueCortical regionMaximum scoreTalairach coordinatesCortical regionBA

RT 126 0.05 L-frontal6.02 −42 40 −19 Middle frontal gyrus11
L-frontal5.59 −46 30 −17 Inferior frontal gyrus47
L-temporal4.83 −48 20 −20 Superior temporal gyrus38

Uncorrected at peak level and , false discovery rate corrected at cluster level, were accepted as statistically significant. In the “cluster level” section on the left, for each cluster found to be statistically significant are reported the number of voxels, the corrected value, and the cortical region where the cluster is found. In the “peak level” section on the right, for each significant cluster are reported the peak coordinates and score, the corresponding cortical region and Brodmann area (BA).