Altered Brain Activation in Early Drug-Naive Parkinson’s Disease during Heat Pain Stimuli: An fMRI Study

Table 4

Decreased activation induced by heat stimulation in patients with PD in contrast to healthy controls.

Region	PD versus control group
	Laterality	BA		MNI coordinates (mm)			Cluster
			Score				(Voxels)
Superior temporal gyrus	L	22	4.51	−63	−27	12	485
Insula	L	47	2.94	−39	18	−6
Middle temporal gyrus	R		3.34	60	−48	15	36
Temporal pole	R	38	3.30	54	6	−12	120
Superior temporal gyrus	R	48	3.25	54	−9	3
Insula	R	48	2.91	48	15	−6