Parkinson’s Disease / 2015 / Article / Tab 2

Research Article

Rapid Screening for Cognitive Impairment in Parkinson’s Disease: A Pilot Study

Table 2

Discriminant indices of MMSE, MoCA, and NINDS-CSN 5-minute protocol cut-off points in discriminating patients with CDR ≥ 0.5 from those with CDR = 0.

MMSEMoCANINDS-CSN 5-minute protocol
Cut-offSENSPECPPVNPVClassifiedCut-offSENSPECPPVNPVClassifiedCut-offSENSPECPPVNPVClassified

25/260.680.680.760.600.6823/240.920.540.740.810.7610/110.930.390.690.800.71
24/250.580.780.800.560.6622/230.870.630.780.760.779/100.820.610.750.690.73
23/24 0.520.880.860.550.6621/22 0.850.880.910.800.868/9 0.770.780.840.700.77
22/230.420.930.890.520.6220/210.730.950.960.710.827/80.680.930.930.670.78
21/220.381.001.000.530.6319/200.680.950.950.670.796/70.531.001.000.590.72

Note: MMSE = Mini Mental State Examination; MoCA = Montreal Cognitive Assessment; NINDS-CSN = National Institute of Neurological Disease and Stroke-Canadian Stroke Network; CDR = Clinical Dementia Rating; SEN = sensitivity; SPEC = specificity; PPV = positive predicted value; NPV = negative predicted value.
Optimal cut-off score.

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