Clinical Study

Personality Changes after Deep Brain Stimulation in Parkinson’s Disease

Table 2

Comparison of neurological measurements; Unified Parkinson’s Disease Rating Scale motor subscores (UPDRS-III), levodopa equivalent daily dose (LEDD), and dopamine agonist usage, preoperatively and after three months of STN-DBS.

PreoperativelyThree-month follow-up Mean differences (SD) value

UPDRS III off, mean (SD)48.9 (12.4)19.8 (9.7)29.1 (10.7)<0.01
UPDRS III on, mean (SD)15.9 (9.4)12.2 (7.8)3.7 (9.0)0.014
LEDD in mg, mean (SD)1217 (433)636 (327)581 (368)<0.01
Dopamine agonist usage, (%)37 (92.5%)18 (45%)<0.01