Screening for Mild Cognitive Impairment in Parkinson’s Disease: Comparison of the Italian Versions of Three Neuropsychological Tests

Table 2

Characteristics of patients, according to the diagnosis and subtype of PD-MCI (MDS Task Force level II criteria).

	No PD-MCI ()	PD-MCI; ()		Single-domain; PD-MCI ()	Multiple-domain; PD-MCI ()
Age	67.5 ± 11.2	68.9 ± 7.2	n.s.	65.5 ± 7.7	70.8 ± 6.2	n.s.
Sex (M/F)	12/9	15/7	n.s.	7/1	8/6	n.s.
School (y)	8.7 ± 3.1	8.3 ± 2.8	n.s.	9.3 ± 2.6	7.6 ± 2.8	n.s.
Duration (y)	7.8 ± 5.3	12.8 ± 8.1	0.03	13.1 ± 8.6	11.4 ± 8.1	n.s.
H-Y (1–5)	1.9 ± 0.7	2.5 ± 0.6	0.014	2.3 ± 0.8	2.6 ± 0.5	n.s.
UPDRS-III (0–108)	23.3 ± 8.9	30.2 ± 8.4	0.02	27.5 ± 10.2	31.5 ± 9.0	n.s.
Treatment
LD (yes/no)	17/4	20/2	n.s.	7/1	13/1	n.s.
DA (yes/no)	12/9	7/15	n.s.	2/6	5/9	n.s.
MAO-I (yes/no)	4/17	1/21	n.s.	0/8	1/13	n.s.
Total LED (mg)	821 ± 413	889 ± 394	n.s.	893 ± 439	888 ± 384	n.s.
Depression (yes/no)	8/13	9/13	n.s.	3/5	6/8	n.s.

School: education (years); duration: disease duration (years); H-Y: Modified Hoehn and Yahr Staging Scale (range 1–5); UPDRS-III: Unified Parkinson’s Disease Rating Scale part III (range 0–108); LD: levodopa; DA: dopamine agonist; MAO-I: monoamine oxidase inhibitors; LED: levodopa equivalent dose (daily).