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Parkinson’s Disease
Volume 2015, Article ID 936865, 8 pages
Research Article

Deep Brain Stimulation Can Preserve Working Status in Parkinson’s Disease

1Department of Neurology, University of Pécs, Rét Utca 2, Pécs 7623, Hungary
2Department of Neurosurgery, University of Pécs, Rét Utca 2, Pécs 7623, Hungary
3MTA-PTE Clinical Neuroscience MR Research Group, Rét Utca 2, Pécs 7623, Hungary
4Department of Neurology, Kaposi Mór County Hospital, Tallián Gyula Utca 16, Kaposvár 7400, Hungary

Received 30 April 2015; Revised 8 July 2015; Accepted 16 July 2015

Academic Editor: Eng-King Tan

Copyright © 2015 Gabriella Deli et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objectives. Our investigation aimed at evaluating if bilateral subthalamic deep brain stimulation (DBS) could preserve working capability in Parkinson’s disease (PD). Materials. We reviewed the data of 40 young (<60 year-old) PD patients who underwent DBS implantation and had at least 2 years of follow-up. Patients were categorized based on their working capability at time of surgery: “active job” group () and “no job” group (). Baseline characteristics were comparable. Quality of life (EQ-5D) and presence of active job were evaluated preoperatively and 2 years postoperatively. Results. Although similar (approximately 50%) improvement was achieved in the severity of motor and major nonmotor symptoms in both groups, the postoperative quality of life was significantly better in the “active job” group (0.687 versus 0.587, medians, ). Majority (80%) of “active job” group members were able to preserve their job 2 years after the operation. However, only a minimal portion (5%) of the “no job” group members was able to return to the world of active employees (). Conclusions. Although our study has several limitations, our results suggest that in patients with active job the appropriately “early” usage of DBS might help preserve working capability and gain higher improvement in quality of life.