The Effect of Hyperhomocysteinemia on Motor Symptoms, Cognitive Status, and Vascular Risk in Patients with Parkinson’s Disease

Table 2

Correlation between plasma homocysteine levels and demographic and clinical characteristics and serum B12 and folic acid values.

	Homocysteine levels
Age (years)	0.27	0.04
Duration of disease (years)	0.23	0.07
Age of PD onset (years)	0.14	0.30
mHY stage		0.44
UPDRS-II score	0.09	0.48
UPDRS-III score	0.01	0.91
UPDRS tremor subscore	0.11	0.42
UPDRS rigidity subscore	0.18	0.16
UPDRS bradykinesia subscore	−0.01	0.92
UPDRS gait/postural instability subscore	0.02	0.90
MMSE score	0.03	0.85
Vitamin B12 (pg/ml)		0.01
Folic acid (ng/ml)	0.06	0.68

Difference is statistically significant ().
PD: Parkinson’s disease; mHY: modified Hoehn and Yahr Staging Scale; UPDRS: Unified Parkinson’s Disease Rating Scale; MMSE: Mini-Mental State Examination.