Altered Mitochondrial Respiration and Other Features of Mitochondrial Function in Parkin-Mutant Fibroblasts from Parkinson’s Disease Patients

Figure 4

Relative of patient-derived and control fibroblasts. Relative was determined by JC-1 red : green fluorescent emission ratios for each fibroblast cell line in three experimental runs. Fibroblasts from P1 were not available; results pertain to a comparison of P2 and P3 parkin-mutant fibroblast with the three controls. Similar was seen for patient-derived (P) and control (Ct) fibroblasts (). °, outlier; , mitochondrial membrane potential.