5-HT_2A Receptor Binding in the Frontal Cortex of Parkinson’s Disease Patients and Alpha-Synuclein Overexpressing Mice: A Postmortem Study

Table 1

Overview of postmortem brain tissue samples used in binding assay analysis showing sample number, diagnosis/cause of death (COD) (PD patients or controls dead of other nonneurological causes), age at time of death (age (death)), gender, and PMI (postmortem interval). CP = cardiopulmonary and GI = gastrointestinal.

Parkinson’s disease (PD) frontal cortex samples				Controls frontal cortex samples
Diagnosis/COD	Age of death	Gender	PMI	Diagnosis/COD	Age of death	Gender	PMI
PD	71	M	23,42	CP	59	M	61
PD	75	M	26,06	GI	81	F	35
PD	84	F	18,92	CP	58	M	43
PD	77	M	11,23	GI	74	F	24
PD	70	M	24,12	GI	70	F	72
PD	66	M	11,21	GI/cancer	69	M	23
PD	85	F	26,25
Mean	75,4	5 M/2 F	20,2	Mean	68,5	3 M/3 F	43

PMI = postmortem interval: time from death to tissue sample collection.