Altered Spontaneous Brain Activity in Cortical and Subcortical Regions in Parkinson’s Disease

Table 2

Brain regions exhibiting the significant altered ALFF between PD patients and normal controls, with age, gender, education level, head motion, and structural atrophy as covariates.

Regions	BA	Cluster	MNI			T-score
		Size	x	y	z
PD < NC
Rt. insula/inferior frontal gyrus	47	13	45	15	−9	3.78
Lt. thalamus		13	−6	−3	12	3.45
Lt. caudate			−6	6	6	2.60
PD > NC
Rt. medial frontal gyrus	8	20	6	39	48	3.43
	6		6	30	42	3.28
Rt. middle frontal gyrus	9	14	42	45	33	3.30
Rt. superior frontal gyrus	10		45	54	21	3.26