Mini Review: Anticholinergic Activity as a Behavioral Pathology of Lewy Body Disease and Proposal of the Concept of “Anticholinergic Spectrum Disorders”

<div>At the stage of parasympathetic nervous system deterioration, which corresponds to the prodromal stage of LBD, HPA axis hyperactivity gradually worsens but does not reach the level at which AA is induced. Therefore, symptoms related to dysfunction of the parasympathetic nervous system occur in LBD, such as REM behavioral symptoms, syncope, and constipation. Moreover, depression, which is related to HPA axis hyperactivity, also develops.</div>

Parkinson’s Disease

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Figure 2: Mini Review: Anticholinergic Activity as a Behavioral Pathology of Lewy Body Disease and Proposal of the Concept of “Anticholinergic Spectrum Disorders” 

Figure 2 | Mini Review: Anticholinergic Activity as a Behavioral Pathology of Lewy Body Disease and Proposal of the Concept of “Anticholinergic Spectrum Disorders” 