Essential Oils May Lead α-Synuclein towards Toxic Fibrils Formation

Figure 2

Effect of M. communis on the fibrillation of α-Syn. (a) The kinetic of α-Syn fibrillation in the absence (●) and the presence of 1% of M. communis () monitored by ThT fluorescence. The continuous lines represent fits to (1). (b)–(e) AFM images and (f)-(g) far-UV CD spectra of α-Syn incubated without or with M. communis (1% v/v). (b), (c), and (f) are for α-Syn incubated without M. communis; (d), (e), and (g) are for samples incubated with M. communis. (▲) is considered for 7 h and (□) for 24 h incubation. (○) is reflected for fresh monomer protein. The concentration of α-Syn was 70 μM.

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