Variations in Incidence and Prevalence of Parkinson’s Disease in Taiwan: A Population-Based Nationwide Study
Table 2
Independent effects of calendar year, age, sex, insurance premium, and urbanization on the incidence and prevalence of Parkinson’s disease, 2002–2009.
Variables
Incidence rate
Prevalence rate
Crude IRR
95% CI
Adjusted IRR†
95% CI
Crude PRR
95% CI
Adjusted PRR†
95% CI
Calendar year
2002-2003
1.00
1.00
1.00
1.00
2004-2005
1.03
0.99–1.06
1.09
1.07–1.11
1.31
1.29–1.33
1.33
1.29–1.37
2006-2007
1.08
1.04–1.11
1.19
1.16–1.22
1.59
1.57–1.61
1.64
1.57–1.70
2008-2009
1.07
1.03–1.11
1.22
1.18–1.27
1.87
1.84–1.90
1.94
1.88–2.00
Trend test: ,
Trend test: ,
Trend test: ,
Trend test: ,
Age (years)
40–49
1.00
1.00
1.00
1.00
50–59
4.60
4.22–5.02
4.26
3.79–4.78
4.25
4.11–4.40
3.81
3.51–4.14
60–69
21.23
19.58–23.02
16.59
14.04–19.59
22.76
22.06–23.48
16.29
13.25–20.03
70–79
62.08
57.38–67.15
44.35
38.69–50.84
64.01
62.10–65.99
42.30
36.15–49.49
≥80
72.81
67.17–78.91
52.24
47.19–57.82
64.55
62.56–66.61
41.48
35.75–48.12
Trend test: ,
Trend test: ,
Trend test: ,
Trend test: ,
Sex
Male
1.09
1.06–1.11
1.05
0.98–1.13
1.09
1.08–1.10
1.08
1.02–1.14
Female
1.00
1.00
1.00
1.00
Insurance premium (NTD)
Dependents
3.13
3.04–3.22
1.50
1.39–1.63
3.45
3.42–3.49
1.66
1.49–1.85
<Median (19,200)
2.46
2.38–2.54
1.56
1.36–1.79
2.67
2.64–2.71
1.71
1.51–1.94
≥Median
1.00
1.00
1.00
1.00
Urbanization
Urban
1.00
1.00
1.00
1.00
Satellite
1.20
1.17–1.24
1.06
1.04–1.09
1.22
1.21–1.24
1.11
1.08–1.13
Rural
1.52
1.45–1.58
1.11
1.05–1.18
1.55
1.52–1.58
1.21
1.13–1.29
Note: inconsistency between the total population and population summed for individual variables was due to missing information. †Estimated from the multivariate Poisson regression with GEE model, which simultaneously included the calendar year, age, sex, insurance premium, and urbanization. . IRR: incidence rate ratio; PRR: prevalence rate ratio; CI: confidence interval. NTD: New Taiwan Dollar; 1 USD ≈ 30 NTD.