Characteristics of Nonmotor Symptoms in Progressive Supranuclear Palsy

Table 2

Frequency of NMS and mean NMSS scores in PSP and HC.

NMSS domain	Frequency of NMS		value	NMSS score		value
	PSP, (%)	HC, (%)		PSP, mean ± SD	HC, mean ± SD
Cardiovascular	5 (18.5)	5 (18.5)	1.000	1.2 ± 3.5	0.3 ± 0.6	0.497
Sleep/fatigue	27 (100)	16 (59.3)	<0.001	12.4 ± 9.5	3.0 ± 4.5	<0.001
Mood/apathy	27 (100)	3 (11.1)	<0.001	16.6 ± 15.4	0.9 ± 3.1	<0.001
Perceptual problems/hallucinations	4 (14.8)	2 (7.4)	0.669	0.2 ± 0.6	0.2 ± 0.8	0.705
Attention/memory	26 (96.3)	16 (59.3)	0.002	7.1 ± 7.4	1.7 ± 2.5	<0.001
Gastrointestinal	23 (85.2)	8 (29.6)	<0.001	7.1 ± 7.0	1.1 ± 2.1	<0.001
Urinary	20 (74.1)	18 (66.7)	0.766	4.7 ± 5.5	3.0 ± 3.3	0.288
Sexual dysfunction	25 (92.6)	13 (48.1)	0.001	6.5 ± 6.7	1.8 ± 1.9	0.001
Miscellaneous	23 (85.2)	10 (37.0)	0.001	5.7 ± 5.6	1.8 ± 3.9	0.002
Total	27 (100)	25 (92.6)	0.491	61.6 ± 31.5	13.7 ± 11.8	<0.001

NMS: nonmotor symptoms. NMSS: Nonmotor Symptoms Scale. PSP: progressive supranuclear palsy. HC: healthy control. SD: standard deviation. Significant difference.