Programming for Stimulation-Induced Transient Nonmotor Psychiatric Symptoms after Bilateral Subthalamic Nucleus Deep Brain Stimulation for Parkinson’s Disease

Table 3

The stimulation parameters and STPS.

Number of PD Patients	Status	STPS times	Chief complaints and symptoms of STPS	Stimulation pattern	CV/CC	Intensity (V/mA)	Pulse width; (μs)	Frequency (Hz)	Left/right	Cathode	Anode	IPG	Electrode	Active contact location	UPDRS-III score (med off/IPG-on)
(1)	Pre-STPS		IPG-off									Activa RC	3389	Medial STN
	STPS	1	Inexplicable euphoria	Monopolar	CV	2.5	60	160	Left	1	Case				None
	STPS	2	Inexplicable euphoria	Monopolar	CV	2.2	60	160	Left	1	Case				14
	Final			Monopolar	CV	1.9	70	160	Left	1	Case				14
(2)	Pre-STPS			Monopolar	CV	2.3	80	140	Left	1	Case	Activa RC	3389	Medial part of STN
				Monopolar	CV	2.5	90	140	Right	9	Case
	STPS	1	Wail	Monopolar	CV	2.5	90	140	Left	1	Case				13
	Final			Bipolar	CV	2.6	90	140	Left	1	2				13
(3)	Pre-STPS			Monopolar	CV	2.5	60	150	Right	9	Case	Activa RC	3389	Medial Inferior part of STN
				Monopolar		2.3	60	150	Left	2	Case
	STPS	1	Hallucination	Monopolar	CV	2.9	70	150	Right	9	Case				25
	STPS	2	Hallucination	Monopolar		2.6	90	130	Right	9	Case				23
	Final			Interleaving	CV	2.5	90	125	Right	2	Case				23
						1.8	70	125		3
(4)	Pre-STPS			Monopolar	CV	2.3	100	90	Left	1	Case	Activa RC	3389	Inferior part of STN/substantia nigra
				Monopolar	CV	2.5	110	90	Right	10	Case
	STPS	1	Hypomania	Double polar	CV	2.4	100	90	Left	0,1	Case				25
	STPS	2	Hypomania	Double polar	CV	2.2	110	85	Left	0,1	Case				25
	Final			Interleaving	CV	2.0	100	90	Left	0	Case				25
						2.3	100	90		1
(5)	Pre-STPS			IPG off								Activa PC	3389	Lateral part of STN/Close to Zona incerta
	STPS	1	Wail	Monopolar	CC	1.9	60	140	Right	10	Case				None
	STPS	2	Wail	Monopolar	CC	1.7	60	130	Right	10	Case				13
	STPS	3	Wail	Bipolar	CC	1.8	60	130	Right	10	11				13
	Final			Monopolar	CC	1.9	60	130	Right	11	Case				13
(6)	Pre-STPS			Double-polar	CV	2.5	60	160	Left	0,1	Case	Activa RC	3389	Inferior part of STN/Close to substantia nigra
				Monopolar	CV	2.7	70	160	Right	9	Case
	STPS	1	Hypomania	Double polar	CV	2.8	60	160	Left	0,1	Case				40
	STPS	2	Hypomania	Interleaving	CV	2.5	80	125	Left	0	Case				39
						2.8	80	125		1	Case
	Final			Interleaving	CV	2.5	70	125	Left	0	Case				41
						2.7	80	125		1,2	Case
(7)	Pre-STPS			Monopolar	CC	2.1	60	145	Left	3	Case	Activa RC	3389	Lateral part of STN/Close to Internal capsule
				Monopolar	CC	2.0	70	145	Right	10	Case
	STPS	1	Inexplicable euphoria	Monopolar	CC	2.1	60	145	Left	3	Case				40
	STPS	2	Inexplicable euphoria	Monopolar	CC	1.9	70	145	Left	3	Case				38
	Final			Bipolar	CV	2.3	70	145	Left	3	2				38
(8)	Pre-STPS			Monopolar	CV	2.6	60	150	Left	1	Case	Activa RC	3389	Medial part of STN
				Monopolar	CV	2.5	60	150	Right	10	Case
	STPS	1	Hypomania	Monopolar	CV	3.1	60	150	Left	1	Case				40
	STPS	2	Hypomania	Monopolar	CV	2.8	70	145	Left	1	Case				40
	Final			Monopolar	CV	3	60	140	Left	2	case				40
(9)	Pre-STPS			Monopolar	CV	2.7	90	160	Right	9	Case	Activa RC	3389	Lateral part of STN
				Double-polar	CV	2.5	80	160	Left	2,3	Case
	STPS	1	Hypomania	Monopolar	CV	3.2	90	160	Right	9	Case				25
	Final			Monopolar	CV	2.9	110	130	Right	9	Case				24
(10)	Pre-STPS			Monopolar	CC	2.0	60	160	Right	9	Case	Activa PC	3389	Medial part of STN
				Monopolar	CC	2.2	60	160	Left	2	Case
	STPS	1	Abnormal spatial orientation	Monopolar	CC	2.2	60	160	Right	9	Case				26
	STPS	2	Abnormal spatial orientation	Monopolar	CC	2.0	70	140	Right	9	Case				25
	Final			Interleaving	CV	2.8	60	125	Right	9	Case				25
						2.1	60	125		10	Case
(11)	Pre-STPS			Monopolar	CV	2.8	70	135	Left	2	Case	Activa RC	3389	Lateral part of STN
				Monopolar	CV	2.5	60	135	Right	10	Case
	STPS	1	Hypomania	Monopolar	CV	3.0	70	135	Left	2	Case				34
	Final			Monopolar	CV	2.7	80	135	Left	2	Case				34

CV, constant voltage; CC, constant current. The patients with no UPDRS-III score (med-off/IPG-on) because they were in the first programming and have not been evaluated with UPDRS- III score yet.