Genetic Variations and mRNA Expression of NRF2 in Parkinson’s Disease

Table 2

Results from genotype and allele analysis.

	Controls% ()	PD% ()	(DF)	OR (95% CI)	value
rs35652124
AA	47.7 (230)	45.0 (215)	0.79 (2)		0.68
AG	43.6 (210)	45.4 (217)
GG	8.7 (42)	9.6 (46)
A	69.5 (670)	67.7 (647)		1.09 (0.90–1.32)	0.40
G	30.5 (294)	32.3 (309)
rs6706649
GG	80.0 (387)	80.2 (385)	0.011 (2)		0.99
GA	18.6 (90)	18.3 (88)
AA	1.4 (7)	1.5 (7)
G	89.3 (864)	89.4 (858)		0.99 (0.74–1.32)	0.94
A	10.7 (104)	10.6 (102)
rs6721961
CC	74.8 (365)	77.4 (370)	2.39 (2)		0.30
CA	24.6 (120)	21.3 (102)
AA	0.6 (3)	1.3 (6)
C	87.1 (850)	88.1 (842)		0.91 (0.70–1.20)	0.54
A	12.9 (126)	11.9 (114)
rs2001350
AA	80.5 (388)	79.5 (387)	2.66 (2)		0.26
AG	19.3 (93)	19.5 (95)
GG	0.2 (1)	1.0 (5)
A	90.1 (869)	89.2 (869)		1.12 (0.82–1.48)	0.55
G	9.9 (95)	10.8 (105)

: number of individuals; PD: Parkinson’s disease; : chi square; DF: degrees of freedom; OR: odds ratio; 95% CI: 95% confidence interval.