Effect of a Traditional Chinese Herbal Medicine Formulation on Cell Survival and Apoptosis of MPP⁺-Treated MES 23.5 Dopaminergic Cells

Figure 1

Effect of CRJ on the cell survival in MPP⁺-treated MES23.5 dopaminergic neurons. (a) Exposure of MPP⁺ alone for 24 or 48 hours resulted in the decrease of cell survival in MES23.5 cells. Posttreatment of different concentration of CRJ for (b) 24 or (c) 48 hours in MPP⁺-treated MES23.5 cells enhanced the cell survival as compared to the MPP⁺ treatment group without CRJ treatment. Data were represented as mean ± SEM in three independent experiments. , MPP⁺-treated cells as compared to control. , , CRJ + MPP⁺ groups as compared to MPP⁺-treated cells. , CRJ + MPP⁺ groups as compared to control.

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