Identification of NURR1 (Exon 4) and FOXA1 (Exon 3) Haplotypes Associated with mRNA Expression Levels in Peripheral Blood Lymphocytes of Parkinson’s Patients in Small Indian Population

Table 5

Mean values (±SEM) of mRNA expression () with PCR-SSCP patterns of NURR1 and FOXA1 gene.

Gene	Gender	Condition		SSCP patterns		Significance
				PCR1	PCR2
NURR1	Male	HC	1.208	A	B	<0.05
		PD	0.508	D	B (0.2)
					D (0.8)
	Female	HC	1.13	B	B	NS
		PD	0.80	B	B
FOXA1	Male	HC	1.327	C	B	<0.05
		PD	0.4884	B	A
	Female	HC	1.681	D	D	NS
		PD	0.7436	D	D

Note. NS represents “not significant” and B (0.2) and D (0.8) show frequency of the patterns B and D
PCR1: PCR amplification of exons in reaction 1; PCR2: PCR amplification of exons in reaction 2.