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Parkinson’s Disease
Volume 2017, Article ID 6139716, 9 pages
Review Article

Quantitative Analysis of Motor Status in Parkinson’s Disease Using Wearable Devices: From Methodological Considerations to Problems in Clinical Applications

1Department of Neurology, Katsushika Medical Center, Jikei University School of Medicine, Tokyo, Japan
2Medical Education Promotion Center, Tokyo Medical University, Tokyo, Japan
3MCHC R&D Synergy Center, Inc., Yokohama, Japan

Correspondence should be addressed to Masahiko Suzuki; moc.liamg@dhpdmikuzus

Received 5 January 2017; Revised 23 March 2017; Accepted 27 April 2017; Published 18 May 2017

Academic Editor: Maral M. Mouradian

Copyright © 2017 Masahiko Suzuki et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Long-term and objective monitoring is necessary for full assessment of the condition of patients with Parkinson’s disease (PD). Recent advances in biotechnology have seen the development of various types of wearable (body-worn) sensor systems. By using accelerometers and gyroscopes, these devices can quantify motor abnormalities, including decreased activity and gait disturbances, as well as nonmotor signs, such as sleep disturbances and autonomic dysfunctions in PD. This review discusses methodological problems inherent in wearable devices. Until now, analysis of the mean values of motion-induced signals on a particular day has been widely applied in the clinical management of PD patients. On the other hand, the reliability of these devices to detect various events, such as freezing of gait and dyskinesia, has been less than satisfactory. Quantification of disease-specific changes rather than nonspecific changes is necessary.