Research Article

Evolution of Orofacial Symptoms and Disease Progression in Idiopathic Parkinson’s Disease: Longitudinal Data from the Jönköping Parkinson Registry

Table 1

Baseline, demographic, and clinical characteristics of the study population with idiopathic Parkinson’s disease (IPD) ().

CharacteristicValue

Sex-male (%)61.5%
Age (at baseline) (yr) mean (SD)64.7 (9.9)
Disease duration (yr) mean (SD)6.6 (5.5)
Follow-up time (yr) mean (SD)3.5 (2.9)
Baseline symptoms (%)
 Resting tremor76.9%
 Bradykinesia73.4%
 Rigidity76.2%
 Fall18.2%
 Freezing13.3%
 Dyskinesia23.8%
 Wearing off14.7%
 Postural instability8.4%
 Visual impairment19.6%
 Hyposmia9.1%
 Urinary urgency21.7%
 Orthostatic hypotension12.6%
 Voice changes16.8%
 Depression18.2%
UPDRS score (at baseline) mean (SD)
 Part I0.8 (1.3)
 Part II9.3 (5.0)
 Part III21.7 (12.3)
 Part IV0.5 (1.7)
 Total32.3 (15.0)
Type of medication (%)
 Levodopa85.3%
 Dopamine agonist49.2%
 MAO-B inhibitor13.2%
 Other dopaminergics5.6%
Orofacial symptoms (during follow-up) (%)
 Drooling55.3%
 Speech problems65.5%
 Swallowing difficulties34.5%
 Facial expression91.6%

SD: standard deviation; UPDRS: Unified Parkinson’s Disease Rating Scale.