Research Article

Oral Health of Parkinson’s Disease Patients: A Case-Control Study

Table 1

Studies on Parkinson’s disease and oral health, available in the international literature.

PublicationCountryResearch designPopulationResults of PD patients when compared to controlsOR95% CIP

Nakayama et al., 2004 [19]JapanQuestionnaire survey by mail104 with PD
191 controls
Gender- and age-adjusted:
More chewing difficulties6.02.8–12.8
More denture discomfort3.91.9–8.0
More edentulousness3.51.8–6.8
Less daily denture care10.52.9–37.3
50% swallowing problems

Schwarz et al., 2006 [20]GermanyCase-control, age-matched70 with PD
85 controls
Higher scores on indices of the Community Periodontal Index for Treatment Needs (CPITN)<0.05

Einarsdóttir et al., 2009 [21]IcelandCase-control67 with PD
55 controls
Lower number of teeth<0.036
More dental carious lesions<0.007
More biofilm3.131.4–6.9<0.004
Poorer periodontal health2.281.0–4.90.035
Greater number of cariogenic bacteria in saliva<0.05

Hanaoka and Kashihara, 2009 [22]JapanCase-control, age-matched89 with PD
68 mild cognitively
impaired
60 with ischemic stroke
Lower number of teeth<0.05
More dental carious lesions<0.001
More deep periodontal<0.001
pockets

Bakke et al., 2011 [23]DenmarkCase-control, age-matched, gender-matched15 with moderate to advanced PD
15 controls
Overall objective orofacial function<0.001
Poorer subjective masticatory ability<0.001
Poorer active mouth opening<0.001
More negative impact of oral health on daily life<0.001

Müller et al., 2011 [24]GermanyCase-control101 with PD
75 controls
Lower gingival index<0.001
Lower frequency of daily tooth brushing<0.01
More dental carious lesions<0.01
Longer time since last dental visit<0.001
Lower salivary flow rate<0.001
More gingival recession<0.001
More tooth mobility<0.001

Cicciù et al., 2012 [25]ItalyCase-control, age-matched45 with mild to moderate PD
45 controls
More dental carious lesionsnot reported
Higher gingival indexnot reported
Higher sulcus bleeding indexnot reported
Higher biofilm indexnot reported

Pradeep et al., 2015 [26]IndiaCase-control, age-matched45 with PD
46 controls
More periodontal pockets<0.001
More periodontal attachment loss<0.001
Lower gingival index<0.001
Lower biofilm index<0.001

Ribeiro et al., 2016 [27]BrasilCase-controlWearers of complete removable dental prostheses 17 with PD
20 controls
Poorer self-perception of oral health<0.04

Barbe et al., 2017 [28]GermanyQuestionnaire survey100 with PD
Frequencies compared with results of other studies
Poorer oral health impact profile, among others due to complaints of xerostomia, drooling and dysphagia