Research Article

Evaluating the Potential of Portulaca oleracea L. for Parkinson’s Disease Treatment Using a Drosophila Model with dUCH-Knockdown

Figure 1

The antioxidant capacity and toxicity of P. oleracea L. extract. (a, b) The antioxidant capacities of PWE and vitamin C were evaluated by DPPH assay. (a) Vitamin C, R2 = 0.9915, IC50 = 13.67 ± 2.03 μM; (b) PWE, R2 = 0.994, IC50 = 72.56 ± 3.03 μg/mL (n = 3 and error bars represent the standard deviation of data); (c) effects of the purslane extracts on survival rate of one-day-old adult fly. Control line TH-GAL4 (w/y; +; TH-GAL4/+) and dUCH-knockdown line TH > dUCH-IR (w/y; +; TH-GAL4/UAS-dUCH-IR). Relative percent survival was calculated as follows: number of adult flies at each concentration of purslane extracts divided by number of nontreated adult flies (population size N = 70 and biological replication n = 2; error bars represent the standard deviation of data).