Polymorphisms of ACMSD-TMEM163, MCCC1, and BCKDK-STX1B Are Not Associated with Parkinson’s Disease in Taiwan

Table 3

Genetic models of single nucleotide polymorphisms (SNPs) in Parkinson's disease (PD) patients and controls.

SNP	Genotype	PD, N = 599; (N, %)	Controls, N = 598; (N, %)	OR (95% CI)	value
ACMSD-TMEM163 rs6430538	TT	584 (97.5)	578 (96.7)
	TC	14 (2.3)	20 (3.3)	0.69 (0.35∼1.38)	0.30
	CC	1 (0.2)	0
Dominant model	CC + TC vs TT	15 (2.5)	20, (3.3)	0.74 (0.38∼1.46)	0.39
Recessive model	CC vs TC + TT	1 (0.16)	0	1.02 (1.00∼1.10)
MCCC1 rs12637471	AA	197 (32.9)	192 (32.1)
	GA	293 (48.9)	295 (49.3)	0.97 (0.75∼1.25)	0.80
	GG	109 (18.2)	111 (18.6)	0.96 (0.69∼1.33)	0.79
Dominant model	GG + GA vs AA	402 (67.1)	406 (67.9)	0.97 (0.76∼1.23)	0.77
Recessive model	GG vs GA + AA	109 (18.2)	111 (18.6)	0.98 (0.73∼1.31)	0.87
BCKDK-STX1B rs14235	AA	483 (80.6)	488 (81.6)
	GA	113 (18.9)	105 (17.6)	1.09 (0.81∼1.46)	0.58
	GG	3 (0.5)	5 (0.8)	0.61 (0.14∼2.55)	0.49
Dominant model	GG + GA vs AA	116 (19.4)	110 (18.4)	1.07 (0.80∼1.42)	0.67
Recessive model	GG vs GA + AA	3 (0.5)	5 (0.8)	0.60 (0.14∼2.51)	0.48

SNP: single nucleotide polymorphism; OR: odds ratio; CI: confidence interval.