Polymorphisms of ACMSD-TMEM163, MCCC1, and BCKDK-STX1B Are Not Associated with Parkinson’s Disease in Taiwan
Table 4
Comparisons of minor allelic and genotypic frequencies of single nucleotide polymorphisms (SNPs) between female and male Parkinson's disease (PD) patients and the controls.
Minor allele of each SNP
PD (N, %)
Controls (N, %)
OR (95% CI)
value
Female (allele)
556
636
ACMSD-TMEM163 rs6430538, C
9 (1.6)
8 (1.3)
1.29 (0.49∼3.37)
0.60
TT
270 (97.1)
310 (97.5)
TC
7 (2.5)
8 (2.5)
1.01 (0.36∼2.81)
0.99
CC
1 (0.4)
0
MCCC1 rs12637471, G
251 (45.1)
277 (43.6)
1.07 (0.85∼1.34)
0.58
AA
83 (29.9)
99 (31.1)
GA
139 (50.0)
161 (50.6)
1.03 (0.71∼1.49)
0.88
GG
56 (20.1)
58 (18.2)
1.15 (0.72∼1.84)
0.56
BCKDK-STX1B rs14235, G
60 (10.8)
61 (9.6)
1.14 (0.78∼1.66)
0.49
AA
219 (78.8)
260 (81.8)
GA
58 (20.9)
55 (17.3)
1.25 (0.83∼1.89)
0.28
GG
1 (0.4)
3 (0.9)
0.40 (0.04∼3.83)
0.41
Male (allele)
642
560
ACMSD-TMEM163 rs6430538, C
7 (1.1)
12 (2.1)
0.50 (0.20∼1.29)
0.14
TT
314 (97.8)
268 (95.7)
TC
7 ((2.2)
12 (4.3)
0.50 (0.19∼1.28)
0.14
CC
0
0
MCCC1 rs12637471, G
260 (40.5)
240 (42.9)
0.91 (0.72∼1.14)
0.41
AA
114 (35.5)
93 (33.2)
GA
154 (48.0)
134 (47.9)
0.94 (0.66∼1.34)
0.72
GG
53 (16.5)
53 (18.9)
0.82 (0.51∼1.30)
0.39
BCKDK-STX1B rs14235, G
59 (9.2)
54 (9.6)
0.95 (0.64∼1.40)
0.79
AA
264 (82.2)
228 (81.4)
GA
55 (17.1)
50 (17.9)
0.95 (0.62∼1.45)
0.81
GG
2 (0.6)
2 (0.7)
0.86 (0.12∼6.18)
0.88
SNP: single nucleotide polymorphism; OR: odds ratio; CI: confidence interval.
