Analysis of the Relationship between Type II Diabetes Mellitus and Parkinson’s Disease: A Systematic Review

Table 1

Relations of descriptors and studies found in PubMed database.

Descriptors	Number of articles
Parkinson’s disease × diabetes mellitus	335
Parkinson’s disease × insulin resistance	39
Alpha-synuclein × diabetes mellitus	19
Alpha-synuclein × insulin resistance	5
Islet amyloid polypeptide × Parkinson’s disease	5
Metformin × Parkinson’s disease	9
Sulfonylurea × Parkinson’s disease	16
Thiazolidinediones × Parkinson’s disease	19
GLP-1 × Parkinson’s disease	7
Bromocriptine × diabetes mellitus	98
Exenatide × Parkinson’s disease	19
Levodopa × diabetes mellitus	54
Dipeptidyl-peptidase IV inhibitors × Parkinson’s disease	2
Sodium-glucose transporter 2 inhibitors × Parkinson’s disease	0