Rate of Progression in Activity and Participation Outcomes in Exercisers with Parkinson’s Disease: A Five-Year Prospective Longitudinal Study

Table 3

Adjusted progression rates (in % of maximum score per year or % of baseline score per year).

	Progression rate per year
	Over 1 year; % (95% CI)	Over 2 years; % (95% CI)	Over 5 years; % (95% CI)
6MWT	7.3 (2.8, 11.8)	2.1 (−0.5, 4.7)	−1.2 (−2.4, −0.03)
Mini-BESTest	−1.7 (−4.0, 0.6)	−0.9 (−2.5, 0.7)	−1.6 (−2.7, −0.6)
UPDRS II	0.6 (−1.3, 2.5)	1.0 (−0.0, 2.1)	1.1 (0.3, 1.9)
PDQ-39 summary index	−1.3 (−3.3, 0.8)	−0.7 (−1.8, 0.4)	0.7 (−0.1, 1.4)

% of baseline score per year; ; . 6MWT = six-minute walk test; Mini-BESTest = Mini-Balance Evaluations System Test; UPDRS = unified Parkinson’s disease rating scale; PDQ-39 = 39-item Parkinson’s disease questionnaire.A negative percentage indicates a progression (decline) in scores for the following measures: 6MWT and Mini-BESTest. A positive percentage indicates a progression (decline) in scores for the following measures: UPDRS II and PDQ-39 (with the opposite sign indicating improvement of symptoms).