Kinematic Metrics from a Wireless Stylus Quantify Tremor and Bradykinesia in Parkinson’s Disease

Table 1

GEE estimates and empirical standard errors, regressing kinematic measures on TREMOR subscale, controlling for medication and DBS status.

	Estimate	SE	Z
RMSrest Vel (%)	0.89	0.14	6.51	<0.0001
RMSpostural Vel (%)	0.75	0.06	12.12	<0.0001
RMSSMT Acc (m/sec^2)	0.03	0.01	5.11	<0.0001
RMSSMT Vel (m/sec)	8.26	3.31	2.49	0.01
Peak Acc (m/sec^2)	0.16	0.07	2.37	0.02
Peak Vel (m/sec)	28.01	14.91	1.88	0.06
Dwell time (sec)	0.02	0.02	1.18	0.24
Frequency (Hz)	0.28	1.13	0.25	0.80
CV dwell time (%)	0.03	0.04	0.59	0.40

Metric with a logarithmic relationship; significant metric (p < 0.05).