Research Article

Balance and Gait Improvements of Postoperative Rehabilitation in Patients with Parkinson’s Disease Treated with Subthalamic Nucleus Deep Brain Stimulation (STN-DBS)

Table 3

The effects of operation and rehabilitation with stimulation.

PREPOSTDISC value Friedman test value (PRE-POST) value (POST-DISC) value (PRE-DISC)

Mini-BESTTest, median (IQR)
Total score19.0 (5.75)19.0 (5.5)23.1 (5.5)<0.010.12<0.01<0.01
Subscore, APA4.0 (1.75)4.0 (1.75)5.0 (1.0)<0.010.84<0.01<0.01
Subscore, reactive2.5 (4.5)2.0 (2.75)4.0 (3.5)0.0380.520.0170.065
Subscore, sensory4.5 (2.5)5.0 (2.75)6.0 (1.0)0.0350.640.042<0.01
Subscore, dynamic gait8.0 (1.0)9.0 (2.0)9.0 (1.75)0.0110.840.0310.016
LEDD (mg), median (IQR)1216 (614)1216 (508)555 (315)<0.010.87<0.01<0.01

PREPOSTDISC value ANOVAF value (PRE-POST) value (POST-DISC) value (PRE-DISC)

TUG (seconds), mean (SD)9.8 (3.9)10.1 (4.2)8.1 (2.3)<0.015.950.91<0.010.026
TUG-cognitive (seconds), mean (SD)16.2 (7.3)16.6 (11.9)11.9 (6.1)0.0115.320.960.0160.031

PREDISCp value Wilcoxon signed-rank test

UPDRS-III17.5 (7.75)13.5 (9.75)0.45
UPDRS-III cardinal score10 (3.5)7.5 (7.75)0.31
UPDRS-III PIGD score2 (2.5)1.5 (2.75)0.49
BI, median (IQR)82.5 (17.5)90.0 (25.0)0.22

IQR, interquartile range; SD, standard deviation; Mini-BESTest, Mini-Balance Evaluation Systems Test; PRE, preoperation; POST, postoperation; DISC, discharge; LEDD, levodopa equivalent daily dose; TUG, Timed Up and Go test; UPDRS-III, unified Parkinson’s disease rating scale motor score; UPDRS-III cardinal score, unified Parkinson’s disease rating scale motor score-cardinal score (20–26); UPDRS-III PIGD score, unified Parkinson’s disease rating scale motor score-postural instability and gait disability score (29-30); BI, Barthel Index. and are and for intergroup comparisons.