Neuroinflammation and Myelin Status in Alzheimer’s Disease, Parkinson’s Disease, and Normal Aging Brains: A Small Sample Study

Table 1

Demographic and neuropathological features of subjects with PD or AD and age-matched controls.

Age (year)	Gender	Onset (years)	STN-DBS (years)	Clinical cause of death	Brain weight (g)	PMI (h)	Braak PD	Braak Aβ	Braak NFT	Diagnosis
84	F	67	0	Inanition	1190	8	5	0	2	PD
87	M	72	0	Inanition	1300	7.7	5	1	1	PD
73	M	58	0	Unknown	1500	52	5	1	2	PD
86	M	63	0	Inanition	1270	15	4	1	2	PD
76	M	66	75	Myocardial infarction	1400	40.5	5	0	1	PD
83	F	69	0	Inanition	900	10.5	0	5	5	AD
93	M	81	0	Inanition	1450	16	0	5	6	AD
85	M	75	0	Inanition	1130	16.5	0	5	5	AD
76	M	67	0	Inanition	1384	28	0	4	6	AD
75	M	67	0	Myocardial infarction	1430	6.5	0	3	3	AD
69	M	60	0	Non-Hodgkin’s lymphoma	1350	21	0	4	6	AD
78	M	N/A	0	Pneumonia	1220	14	0	0	1	NC
78	M	N/A	0	Metastatic prostate cancer	1208	87	0	0	1	NC
78	F	N/A	0	Duodenal cancer	1290	15.7	0	0	2	NC
91	M	N/A	0	Septicemia	1250	16	0	0	2	NC

STN-DBS, subthalamic nucleus-deep brain stimulation; PMI, postmortem interval; Braak PD, Braak Lewy body stages in Parkinson’s disease (range: 1–6); Braak Aβ, Braak beta-amyloid plaque stage; Braak NFT, Braak neurofibrillary tangle stage; PD, Parkinson’s disease; AD, Alzheimer’s disease; NC, age-matched cognitively intact normal control.