Automated Subfield Volumetric Analysis of Hippocampus in Patients with Drug-Naïve Nondementia Parkinson’s Disease

Table 1

Demographic and clinical characteristics of patients with drug-naïve nondementia Parkinson’s disease and healthy controls.

	HC ()	PD ()	value
Age (years)	69.5 ± 6.3	68.25 ± 7.22	0.606
Sex (%, female)	13 (81.3%)	13 (81.3%)	1.000
MMSE	27.90 ± 1.2	27.40 ± 1.24	0.073
TICV (mm^3)	1415.40 ± 103.40	1395.26 ± 162.12	0.678
Disease duration (years)	—	2.59 ± 2.08	—
UPDRS (part III)	—	15.63 ± 5.81	—
H&Y stage	—	1.72 ± 0.63	—
Dominantly affected side (right : left)	—	12 : 4	—
Right handed	16	16	—

Data are the mean ± standard deviation in age, MMSE scores, and TICV. The values for comparison in age, MMSE scores, and TICV were obtained by independent t-tests. The values for distribution of sex were obtained by chi-square tests. HC, healthy control group; PD, Parkinson’s disease group; MMSE, mini-mental status examination; TICV, total intracranial cavity volume.