Research Article

Automated Subfield Volumetric Analysis of Hippocampus in Patients with Drug-Naïve Nondementia Parkinson’s Disease

Table 3

Post hoc analysis in the differences of the total and subfield hippocampal volumes between the hemispheres in the diagnosis groups.

SubfieldVolume (mm3)
HCPD
RightLeftFRightLeftF

CA2-3905.50 ± 109.62907.39 ± 153.150.0050.946922.81 ± 103.26851.60 ± 87.2019.911<0.001
CA4-DG509.05 ± 53.49514.72 ± 87.240.1270.726520.51 ± 58.62480.69 ± 50.3320.273<0.001
Total2801.93 ± 280.202835.81 ± 388.630.2340.6352779.93 ± 323.332637.83 ± 277.8710.5730.005

Data are the mean ± standard deviation (mm3). Repeated-measures analysis of variance tests were performed. HC, healthy control group; PD, Parkinson’s disease, nondementia group; CA, cornu ammonis; DG, dentate gyrus. A significant statistical difference with .