Research Article

Improvement of Blood Plasmalogens and Clinical Symptoms in Parkinson’s Disease by Oral Administration of Ether Phospholipids: A Preliminary Report

Table 4

Increase of erythrocyte plasmalogen in PD after administration of scallop-derived ether phospholipids.

Variable (%)BeforeAfter 12 weeks valueAfter 24 weeks value

plsPE7.67 (0.78)8.43 (1.2)0.038.64 (0.97)0.01
PE9.71 (0.81)10.12 (0.77)0.3210.81 (0.95)0.03
PC23.25 (1.74)23.54 (3.29)0.8325.41 (1.74)0.006
SM49.99 (3.1)47.87 (5.41)0.3944.83 (2.65)0.004
PS9.34(1.14)10.05 (1.08)0.1310.33 (0.75)0.01

Values are mean (SD) unless otherwise specified. plsPE: ethanolamine plasmalogen; PE: diacyl ethanolamine glycerophospholipid; PC: diacyl choline glycerophospholipid; PS: diacyl serine glycerophospholipid; SM: sphingomyelin. Differences from immediate before trial.