LRRK2 Mutations and Asian Disease-Associated Variants in the First Parkinson’s Disease Cohort from Kazakhstan

<div>LRRK2 protein: functional domain and the localization of 8 variants. ANK-ankyrin repeat; ARM-armadillo; LRR-leucine-rich repeat; ROC-Ras of complex proteins: GTPase; COR-C-terminal of ROC; WD40-WD-40 domain. Pathogenic mutations are highlighted in blue, and East Asian disease-associated variants are highlighted in red.</div>

Parkinson’s Disease

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Figure 1

Figure 1: LRRK2 Mutations and Asian Disease-Associated Variants in the First Parkinson’s Disease Cohort from Kazakhstan 