LRRK2 Mutations and Asian Disease-Associated Variants in the First Parkinson’s Disease Cohort from Kazakhstan

Figure 2

Familial case with p.Gly2385Arg variant. III:2 Proband 40 years old, PD onset at 38 years. II:1 Affected mother of the proband. PD onset at 55 years. Died at 58 years. Levodopa responsive PD. II:3 affected maternal aunt. 10 years' history of unilateral right-hand tremor at rest and action. II:5 Affected maternal aunt, 54 years old. 10 years' history of positional unilateral tremor. III:9 son of II:5. Right-hand positional tremor. II:9 Affected maternal aunt, 4-5 years' history of right-hand positional tremor.