LRRK2 Mutations and Asian Disease-Associated Variants in the First Parkinson’s Disease Cohort from Kazakhstan

Table 5

p.Ala419Val-positive PD patients and their characteristics.

	Number 246-4uncalled = 242	Mean age at examination	Mean age of onset	Mean disease duration	Family history	Mean HY stage off
Carriers	9	57.4 ± 12.9	48.3 ± 12.6	9.1 ± 6.1	2	2.5 ± 0.5
Noncarriers	233	61.6 ± 10.4	54.7 ± 12.3	6.8 ± 7	19	2.2 ± 0.7
P value		0.38	0.19	0.3		0.02

HY–Hoehn–Yahr.