| | | Cases | Controls | Ethnicity | OR | MAF for PD patients |
| | Funayama et al., 2007 [13] | 448/52 (11.6%) (2 homozygous cases) | 457/22 (4.8%) | Japanese | OR for the frequency of A allele 2.63, 95% CI: 1.56–4.35, = 1.24 × 10−4 | 0.06 | | Di Fonzo at al., 2006 [6] | 608/61 (10%) | 373/18 (4.8%) | Han Chinese from Taiwan | OR = 2.24, 95% CI: 1.29–3.88, p = 0.004 | 0.05 | | Fung et al., 2006 [17] | 305/27 (9%) | 176/1 (0.5%) | Han Chinese from Taiwan | 16.99, 95% CI: 2.29 to 126.21, | 0.4 No positive cases with FH | | An et al., 2008 [21] | 600/71 (1 homozygous) (11.9%) | 334/11 (3.3%) | Han Chinese | OR 3.9, 95% CI = 2.1–7.5, | 0.06 | | Tan et al., 2007 [18] | 494/37 (7.27%) (1 homozygous) | 495/18 (3.64%) | Ethnic Chinese | OR 2.1, 95% CI: 1.1–3.9, | PAR of 4% for the Gly2385Arg heterozygous genotype. | | Tan et al., 2007 [8] | 166/2 (Malays) | 306/2 (Malays) | Malay 98/173, Indian ethnicity 66/133 | OR 2.83, 95% CI 0.40, 20.2, | 0.003 for Malays | | Farrer et al., 2007 [16] | 410/34 | 335/13 (3.9%) | Ethnic Chinese | OR 2.24 95% CI 1.16–4.32, | MAF 0.08
23.1% (n = 6/26) of patients with familial parkinsonism. | | Ross et al., 2011 [23] | 1,376 | 962 | Japan, Korea, Taiwan | OR: 1.73, 95% CI: 1.20–2.49, | MAF 3.3% | Japan
PD: 173 | Control: 75 | Korea
|PD: 844 | Control: 587 | Taiwan
PD: 369 | Control: 300 | | Mata et al., 2005 [20] | 100 probands with PD FH/2 cases | | Taiwan | 1 family with 2 members | | | Zabetian et al., 2009 [24] | 601/69 (11.5%) | 1628/101 (6.2%) | Japanese | OR, 1.83; 95% CI: 1.31–2.54; = 3.3 × 10−4 | | | Gapalai et al., 2015 [14] | 695 | 507 | Malaysian | OR 2.22 () | MAF = 0.026 |
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