Effect of Intestinal Levodopa-Carbidopa Infusion on Pharyngeal Dysphagia: Results from a Retrospective Pilot Study in Patients with Parkinson’s Disease

Table 2

Descriptive statistics of the FEES-L-dopa-score and its subdomains, white-out duration, levodopa equivalent daily dose (LEDD), Hoehn and Yahr scale, and functional oral intake scale (FOIS), as well as the value of the comparison before and after beginning of levodopa-carbidopa intestinal gel (LCIG) in the total cohort and the subgroup of patients with follow-up FEES before and after beginning with LCIG.

	Before LCIG	After LCIG	value
Mean FEES-L-dopa-score ± SD
Subgroup	14.9 ± 7.3	13.0 ± 6.9	0.312
Mean score premature spillage ± SD
Subgroup	5.4 ± 1.1	3.6 ± 1.0	0.002
Mean score penetration/aspiration ± SD
Subgroup	0.3 ± 0.9	0.5 ± 1.0	0.690
Mean score residue ± SD
Subgroup	9.3 ± 5.9	8.9 ± 6.0	0.795
Mean white-out duration in ms ± SD
Subgroup	984 ± 228	699 ± 131	0.002
Mean Hoehn and Yahr ± SD
Total cohort	3.8 ± 0.7	3.5 ± 0.7	0.078
Subgroup	3.6 ± 0.5	3.8 ± 0.6	0.317
Mean LEDD ± SD
Total cohort	1182.9 ± 339.3	1684.2 ± 468.2	<0.001
Subgroup	1246.1 ± 371.9	2062.0 ± 379.2	<0.001
Mean FOIS ± SD
Total cohort	6.6 ± 1.1	6.6 ± 1.1	0.832
Subgroup	6.4 ± 0.9	6.6 ± 0.5	0.414