Research Article

Association of Tooth Loss with New-Onset Parkinson’s Disease: A Nationwide Population-Based Cohort Study

Table 1

Baseline characteristics of the study population.

CharacteristicsTotal

Number of participants153,165
Age (years)52.8 ± 8.3
Male sex98,434 (64.3)
Income level
 Fifth quintile (highest)62,799 (41.0)
 Fourth quintile30,365 (19.8)
 Third quintile21,386 (14.0)
 Second quintile18,872 (12.3)
 First quintile (lowest)19,479 (12.7)
 Covered by medical aid264 (0.2)
Body mass index (kg/m2)23.9 ± 2.8
Alcohol intake73,523 (48.0)
Smoking status
 Nonsmoker100,075 (65.3)
 Ex-smoker16,721 (10.9)
 Current smoker36,369 (23.7)
Regular physical activity15,062 (9.8)
Comorbidities
 Hypertension52,257 (34.1)
 Diabetes mellitus14,799 (9.7)
 Dyslipidemia25,234 (16.5)
 Renal disease328 (0.2)
 History of malignancy15,337 (10.0)
Blood pressure
 Systolic blood pressure (mmHg)125.8 ± 16.6
 Diastolic blood pressure (mmHg)78.8 ± 10.8
Laboratory findings
 Total cholesterol (mg/dL)197.8 ± 36.1
 Fasting blood glucose level (mg/dL)97.9 ± 27.8
 Aspartate aminotransferase (U/L)26.6 ± 16.1
 Alanine aminotransferase (U/L)25.9 ± 20.2
 Gamma-glutamyl transferase (U/L)40.0 ± 56.1
 Proteinuria (≥1 + in dip stick test)4,948 (3.2)
Oral health status
 Presence of periodontal disease30,580 (20.0)
 Number of tooth loss
  0115,483 (75.4)
  1–734,077 (22.2)
  8–142,147 (1.4)
  ≥151,458 (1.0)
Oral hygiene care
 Dental clinic visits for any causes67,211 (43.9)
 Frequency of tooth brushings (times/day)
  0-121,382 (14.0)
  266,089 (43.1)
  ≥365,694 (42.9)
 Competent dental care40,177 (26.2)

Data are expressed as the mean ± standard deviation or n (%).