Urinary Dysfunction Is Associated with Nigrostriatal Dopaminergic Degeneration in Early and Untreated Patients with Parkinson’s Disease

Table 2

Coefficient of correlation between urinary symptoms and clinical characteristics in patients with PD.

	Storage symptoms		Voiding symptoms
	Unadjusted	Adjusted	Unadjusted	Adjusted
Motor symptoms
PD duration	0.009	0.095	0.051	0.097
Hoehn and Yahr stage	0.166	0.109	0.081	0.016
MDS-UPDRS Part III	0.183	0.135	0.106	0.037
Rigidity	0.165	0.158	0.116	0.062
Postural instability	0.233	0.103	0.117	0.019
Bradykinesia	0.167	0.095	0.070	−0.010
Rest tremor amplitude	0.000	−0.042	0.022	0.002
Constancy of rest tremor	−0.042	−0.077	−0.023	−0.035
Nonmotor symptoms
RBDSQ	0.168	0.168	0.153	0.169
GDS-15	0.227	0.119	0.236	0.148
STAI state	0.071	0.040	0.121	0.112
STAI trait	0.156	0.128	0.176	0.170
ESS	0.207	0.208	0.194	0.149
MoCA	−0.012	0.042	−0.055	0.018
UPSIT	−0.187	−0.165	−0.172	−0.079
DAT binding levels
Caudate
More affected	−0.168	−0.105	−0.153	−0.057
Less affected	−0.196	−0.099	−0.192	−0.069
Putamen
More affected	−0.135	−0.083	−0.099	−0.028
Less affected	−0.291	−0.172	−0.225	−0.119

Adjusted for age and sex; values < 0.05; values < 0.01; values < 0.001.