Evolution of Initial Pharmacologic Treatment of Newly Diagnosed Parkinson’s Disease Patients over a Decade in Singapore

Table 3

Univariate analysis of factors determining the use of LD vs. LD-sparing strategies.

	LD	LD-sparing	value
Age	70.3 ± 8.8	57.5 ± 8.1	<.001
Male, n (%)	91 (54.8)	40 (62.5)	0.292
HY stage, mean (SD)	2.4 (0.7)	1.9 (0.5)	<.001
Mean duration of illness (SD), months	68.9 (61.2)	56.8 (43.6)	0.148
Rest tremor present, n (%)	84 (57.5)	41 (70.7)	0.082

HY, Hoehn and Yahr; LD, levodopa. ^#All characteristics were analyzed as continuous variables except sex and presence of rest tremor. Results of multivariate analysis including all factors listed in the table are reported in the main text.